Daypro
Why is this medication prescribed?
Oxaprozin is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). Oxaprozin is also used to relieve pain, tenderness, swelling, and stiffness caused by juvenile rheumatoid arthritis in children 6 years of age and older. Oxaprozin is in a class of medications called nonsteroidal anti-inflammatory medications (NSAIDs). It works by stopping the body's production of a substance that causes pain, fever, and inflammation.
How should this medicine be used?
Oxaprozin comes as a tablet to take by mouth. It is usually taken once or twice a day. Take oxaprozin at around the time(s) each day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take oxaprozin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking oxaprozin,
tell your doctor and pharmacist if you are allergic to oxaprozin, aspirin, or other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), any other medications, or any of the inactive ingredients in oxaprozin tablets. Ask your pharmacist for a list of the inactive ingredients.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take while taking oxaprozin.Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
the following nonprescription products may interact with oxaprozin: aspirin and nonsteroidal anti-inflammatory drugs (NSAIDS) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve). Be sure to let your doctor and pharmacist know that you are taking these medications before you start taking oxaprozin. Do not start any of these medications while taking oxaprozin without discussing with your healthcare provider.
tell your doctor if you have or ever had asthma, especially if you also have frequent stuffed or runny nose or nasal polyps; heart failure; swelling of the hands, feet, ankles, or lower legs; or kidney or liver disease.
tell your doctor if you are pregnant, plan to become pregnant; or are breast-feeding. Oxaprozin may harm the fetus and cause problems with delivery if it is taken around 20 weeks or later during pregnancy. Do not take oxaprozin around or after 20 weeks of pregnancy, unless you are told to do so by your doctor. If you become pregnant while taking oxaprozin, call your doctor.
talk to your doctor about the risks and benefits of taking oxaprozin if you are 65 years of age or older. Older adults should take lower doses of oxaprozin for only a short time period because higher doses used regularly may not be more effective and are more likely to cause serious side effects.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking oxaprozin.
plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Oxaprozin may make your skin sensitive to sunlight.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Oxaprozin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
diarrhea
constipation
vomiting
gas or bloating
drowsiness
difficulty sleeping
confusion
depression
dizziness
headache
ringing in the ears
Some side effects can be serious. If you experience any of the following symptoms or those mentioned in the IMPORTANT WARNING section, call your doctor immediately. Do not take any more oxaprozin until you speak to your doctor:
unexplained weight gain
shortness of breath or difficulty breathing
swelling in the abdomen, ankles, feet, or legs
fever
blisters
rash
itching
hives
swelling of the eyes, face, lips, tongue, throat, or hands
hoarseness
difficulty breathing or swallowing
yellowing of the skin or eyes
lack of energy
excessive tiredness
upset stomach
loss of appetite
pain in the upper right part of the stomach
flu-like symptoms
pale skin
fast heartbeat
cloudy, discolored, or bloody urine
back pain
difficult or painful urination
Oxaprozin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (https://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about storage and disposal of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Keep all medication out of sight and reach of children as many containers are not child-resistant. Always lock safety caps. Place the medication in a safe location – one that is up and away and out of their sight and reach. https://www.upandaway.org
Dispose of unneeded medications in a way so that pets, children, and other people cannot take them. Do not flush this medication down the toilet. Use a medicine take-back program. Talk to your pharmacist about take-back programs in your community. Visit the FDA's Safe Disposal of Medicines website https://goo.gl/c4Rm4p for more information.
In case of emergency/overdose
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include the following:
lack of energy
drowsiness
upset stomach
vomiting
stomach pain
bloody, black, or tarry stools
vomiting a substance that is bloody or looks like coffee grounds
difficulty breathing
seizures
coma (loss of consciousness for a period of time)
What other information should I know?
Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking oxaprozin.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.
Brand names
Daypro®